View Cart (0)
View Wishlist (0)
Checkout
1-800-586-6038
Premade Lentivirus → Lentiviral sgRNA CRISPR → Lentiviral BAP1 sgRNA CRISPR/Cas9

Lentiviral BAP1 sgRNA CRISPR/Cas9

BAP1 (BRCA1 Associated Protein 1) is a deubiquitylase thought to be a key regulator of many cancer-associated pathways. BAP1 binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. 

This lentivirus expresses human BAP1 sgRNA under the control of the U6 promoter, Cas9 nuclease and puromycin under the control of the EF1a promoter.

Virus: Lentiviral BAP1 sgRNA CRISPR/Cas9
Titer (approx): 1 x 107 TU/ml
Vector Information: Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
Promoter for sgRNA: U6
Promoter for Cas9 nuclease: Ef1a
Species:
 Human
sgRNA target gene:   BAP1
sgRNA Sequence:
 G AAC TCA GCG TCC CGG CCT G
Selection Gene: Puromycin
Biosafety Level: BSL-2
Shipped: Dry ice
Storage: Store at -80°C

User Instructions | Materials Safety Data Sheet | pCRISPR-EF1a-Cas9 vector 

Catalog Number Product Size Price Qty
GT-10002-50
Lentiviral BAP1 sgRNA CRISPR/Cas9 (1x10^7 TU/ml)
 2x25 ul
Price: $490.00
GT-10002-200
Lentiviral BAP1 sgRNA CRISPR/Cas9 (1x10^7 TU/ml)
 8x25 ul
Price: $1,200.00
  • Payment Methods
 
Copyright | 2023 Cellomics Technology, LLC. All Rights Reserved. | 1450 South Rolling Rd., Halethorpe, MD 21227 | 1.800.586.6038
Loading...