SLCO1B1 Full-Length ORF: Human Gene GFP Lentivirus

Gene ID: 10599

Synonym(s): HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6

Description: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009].

There is one cDNA ORF sequence of this gene in the NCBI database that is of the same length as this clone; however, the amino acid sequences are not completely identical. The detailed alignment results are at the bottom of the Product Detail table below. For more detailed information regarding this clone and its ORF, please contact [email protected].