ENO1 Full-Length ORF: Human Gene GFP Lentivirus

Gene ID: 2023

Synonym(s): ENO1-IT1, ENO1L1, HEL-S-17, MPB1, NNE, PPH

Description: This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].

There are several cDNA ORF sequences of this gene in the NCBI database that are of the same length as this clone; however, the amino acid sequences are not completely identical. The detailed alignment results are at the bottom of the Product Detail table below. For more detailed information regarding this clone and its ORF, please contact [email protected].