GSDMB ORF clone

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Gene ID: 55876

Synonym(s): GSDMB-1, GSDML, PP4052, PRO2521

Description: This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016].

There are several cDNA ORF sequences of this gene in the NCBI database that are embedded in this clone; however, the amino acid sequences are not completely identical. The detailed alignment results are at the bottom of the Product Detail table below. For more detailed information regarding this clone and its ORF, please contact tech@cellomicstech.com.

Product Details

Clone Vector	pCT-MSCV-PGK-PruoR Vector
Species	Human
Promotor for Target Gene	CMV
Target Gene Name	GSDMB
Target Gene Position	Inserted between PacI and AscI
ORF Length	1236
Protein Length	411
Native Stop Codon	True
ORF Sequence	atgttcagcgtatttgaggaaatcacaagaattgtagttaaggagatggatgctggaggggatatgattgccgttagaagccttgttgatgctgatagattccgctgcttccatctggtgggggagaagagaactttctttggatgccggcactacacaacaggcctcaccctgatggacattctggacacagatggggacaagtggttagatgaactggattctgggctccaaggtcaaaaggctgagtttcaaattctggataatgtagactcaacgggagagttgatagtgagattacccaaagaaataacaatttcaggcagtttccagggcttccaccatcagaaaatcaagatatcggagaaccggatatcccagcagtatctggctacccttgaaaacaggaagctgaagagggaactacccttttcattccgatcaattaatacgagagaaaacctgtatctggtgacagaaactctggagacggtaaaggaggaaaccctgaaaagcgaccggcaatataaattttggagccagatctctcagggccatctcagctataaacacaagggccaaagggaagtgaccatccccccaaatcgggtcctgagctatcgagtaaagcagcttgtcttccccaacaaggagacgatgagtgctggtttggatattcatttcaggggcaaaacaaaatcctttccagaaggaaagtctttgggttcggaggattccagaaacatgaaggagaagttggaggacatggagagtgtcctcaaggacctgacagaggagaagagaaaagatgtgctaaactccctcgctaagtgcctcggcaaggaggatattcggcaggatctagagcaaagagtatctgaggtcctgatttccagggagctacacatggaggactcagacaagcctctcctaagcagcctttttaatgctgctggggtcttggtagaagcgcgtgcaaaagccattctggacttcctggatgccctcctagagctgtctgaagagcagcagtttgtggctgaggccctggagaaggggacccttcctctgttgaaggaccaggtgaaatctgtcatggagcagaactgggatgagctggccagcagtcctcctgacatggactatgaccctgaggcacgaattctctgtgcgctgtatgttgttgtctctatcctgctggagctggctgaggggcctacctctgtctcttcctga
Protein Sequence	MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISRELHMEDSDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS
Mismatch to NM_001165959	[p.M220_N221insS; p.M220_N221insA; p.M220_N221insG; p.M220_N221insL; p.N221D; p.G295R; p.P302S]
Mismatch to NM_001388421	[p.M220_N221insS; p.M220_N221insA; p.M220_N221insG; p.M220_N221insL; p.N221D; p.G295R; p.P302S]

User Instructions | pCT-MSCV-ORF-PGK-PruoR Vector Map | Materials Safety Data Sheet

Catalog Number	Product	Size	Price	Qty
ET-113934-RV-50	GSDMB Retrovirus Particles (MSCV, PuroR)	2x25 ul per vial, 1x10^8 TU/ml	Price: $700.00	Quantity
ET-113934-RV-200	GSDMB Retrovirus Particles (MSCV, PuroR)	8x25 ul per vial, 1x10^8 TU/ml	Price: $1,200.00	Quantity
ET-113934-RV-pd	GSDMB Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock	1 vial	Price: $1,200.00	Quantity

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GSDMB Full-Length ORF: Human Gene Retrovirus

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